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Antifungal Nifuratel CAS 4936-47-4
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Antifungal Nifuratel CAS 4936-47-4
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 Antifungal Nifuratel CAS 4936-47-4
Product Name: Nifuratel
Synonyms: 5-[(Methylsulfanyl)Methyl]-4-[(E)-[(5-nitrofuran-2-yl)Methylidene]aMino]-1,3-oxazolidin-2-one;3-[(5-Nitro-2-furfurylidene)aMino]-5-[(Methylthio)Methyl]-2-oxazolidinone;5-(MethylMercaptoMethyl)-3-(5-nitro-2-furfurylidenaMino)-2-oxazolidinone;2-Oxazolidinone,5-[(Methylthio)Methyl]-3-[[(5-nitro-2-furanyl)Methylene]aMino]-;MACMIROR;5-[(METHYLTHIO)METHYL]-3-[[(5-NITRO-2-FURANYL)METHYLENE]AMINO-]-2-OXAZO-LIDINONE;5-methylthiomethyl-3-(5-nitrofurfurylideneamino)-2-oxazolidone;NIFURATEL
CAS: 4936-47-4
MF: C10H11N3O5S
MW: 285.28
EINECS: 225-576-2
Nifuratel is a derivative of nitrofuran , it is a broad spectrum antibiotic with broad-spectrum antimicrobial effect, Nystatin is a polyene antifungal,it has strong effects on trichomoniasis, bacteria, Candida albicans , it plays a strong killing role especially in common pathogens for gynecological infections such as gram-positive and gram-negative bacteria, trichomoniasis, mold, chlamydia and mycoplasma . After oral administration, it is absorbed by gastrointestinal ,most of it is excreted through the kidneys, it has higher concentrations in blood, urine, genital tissues ,so it can have a strong antibacterial effect in the urinary system, and its metabolites still have antibacterial activity, and it is excreted through the urine . Oral nifuratel can be rapidly absorbed, after oral administration of 200mg, the peak plasma concentration is 9.48μg/L in two hours . The animals acute toxicity test proves that in toxicity of the product is mild.
 
Chemical Properties Yellow Solid
Uses Nifuratel is a drug used as an antibacterial, antifungal, antiprotozoal (Trichomonas). Nifuratel appears to have a broad antibacterial spectrum of action and is effective against Chlamydia trachomatis and Mycoplasma spp. as well as fungal infections from Candida spp.
Nifuratel is an antibacterial, antifungal, and antiprotozoal compound with activity against Trichomonas.